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In a study published in Science on April 15, researchers at the Weizmann Institute of Science, together with colleagues from the Queen Mary University of London and the Hebrew University of Jerusalem, have revealed the mechanism of action of the master switch for hunger in the brain: the melanocortin receptor 4, or MC4 receptor for short. They have also clarified how this switch is activated by setmelanotide Imcivree , a drug recently approved for the treatment of severe obesity caused by certain genetic changes. These findings shed new light on the way hunger is regulated and may help develop improved anti-obesity medications. The MC4 receptor is present in a brain region called the hypothalamus—within a cluster of neurons that compute the body's energy balance by processing a variety of energy-related metabolic signals. When the MC4 is activated, or "on"—as it normally is—it sends out commands that cause us to feel full, which means that from the brain's perspective, our default state is satiety. The Hunger Games Personal Response
Reuters world news Russia hits back as US warns of response if opposition leader Alexey Navalny dies on hunger strike The US and Europe are pressing Putin to ensure proper medical care for Navalny, who began a hunger strike in prison March 31 to demand access to his personal doctors for acute back and leg pains. Russia should brace for measures aimed at its vital energy sector and industry, he said.
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Amid fears of more potential sanctions, the ruble traded 0. The US and Europe are pressing Putin to ensure proper medical care for Navalny, who began a hunger strike in prison March 31 to demand access to his personal doctors for acute back and leg pains. But we have communicated that there will be consequences if Mr. Navalny has been imprisoned Responwe March 11 at the notorious IK-2 prison camp about kilometers 60 miles from Moscow for breaking parole rules while recuperating in Germany from a The Hunger Games Personal Response poisoning in Siberia that he and Western governments blame on the Kremlin. Russian authorities deny any involvement.
US Sanctions President Joe Biden on Thursday ordered a raft of new sanctions against Russia, including restrictions on buying new sovereign debt, in response to allegations that Moscow was behind a hack on SolarWinds Corp. Yet the moves were calibrated to punish the Kremlin for past behavior while keeping relations from deteriorating further, especially as tensions grow over a Russian military build-up near Ukraine. Officials have said Reponse that Navalny has received all necessary medical attention.]
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