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A Red Light For Scofflaws Summary

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This may cause vascular occlusion and thereby severe pain, organ failure and death. Here, using light and transmission electron microscopy, we demonstrate extensive in vivo sickling of whiting red blood cells after capture stress without any apparent haemolysis and show its subsequent recovery. We show exceptionally high cooperative proton binding during the sickling process in vitroand identify the reduction of extracellular pH below resting values as the primary cause for in vivo sickling, although the response is modulated to a lesser extent also by oxygen tension. We propose that this mechanism protects red blood cells of some fishes against the problem of haemoglobin aggregation and red blood cell sickling, except under most severe acidosis. This system offers a unique example of how, over evolutionary time, nature may have overcome what is still a deadly disease in humans. This is supported by an extremely high Hb concentration inside red blood cells RBCs , which is close to the solubility limit Riggs, A Red Light For Scofflaws Summary

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The steam to the turbines was shut off, beginning a run-down of the turbine generator. The diesel generators started and sequentially picked up loads; the generators were to have completely picked up the MCPs' power needs by In the interim, the power for the MCPs was to be supplied by the turbine generator as it coasted down. As the momentum of the turbine generator decreased, so did the power it produced for the pumps. The water flow rate decreased, leading to increased formation of steam voids in the coolant flowing up through the fuel pressure tubes. The mechanism would be used even to routinely shut down the reactor after the experiment for the planned maintenance [39] and the scram likely preceded the sharp increase in power. The control rod insertion mechanism moved the rods at 0. A bigger problem was the design of the RBMK control rods , each of which had a graphite neutron moderator section attached to its end to boost reactor output by displacing water when the control rod section had been fully withdrawn from the reactor, i. Consequently, injecting a control rod downward into the reactor in a scram initially displaced neutron-absorbing water in the lower portion of the reactor with neutron-moderating graphite.

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A Red Light For Scofflaws Summary

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A Red Light For Scofflaws Summary

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