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Oxford Biomedica plc Preliminary results for the year ended 31 December We not only secured major new partnerships, brought the Oxbox manufacturing facility online in record time and responded to the challenges of the pandemic, but the team has also been able to rapidly work with AstraZeneca to provide a vaccine solution for COVID This is a true testament to the world-class calibre and dedication of our staff in the year that the Group also gained entry to the FTSE Operating expenses is made up out of Bioprocessing expenses, Research and development expenses and Administrative expenses.
A reconciliation to GAAP measures is provided on page Having signed an initial agreement in May, in September the Group signed an month supply agreement under a three-year master supply and development agreement for the large-scale manufacture of the Oxford AstraZeneca COVID vaccine. Collaboration with Novartis continued to strengthen with a sixth vector construct added in the first quarter ofwith partnership having been previously extended by five years in December In August, the Group signed a development, manufacture and licence agreement with Beam Therapeutics for next generation CAR-T programmes including a three-year clinical supply agreement.
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Post period end in Marchthe Group announced that Sanofi had given notice that they intend to terminate the collaboration and licence agreement for the process development and manufacturing of lentiviral vectors to treat haemophilia. The Group expects the impact on revenue will be negligible over the coming 24 month period. Post period end in Aprilthe Group signed a three-year development and supply agreement with Boehringer Ingelheim for the manufacture and supply of viral vectors, building on the partnership that started in Building work at Windrush Court to convert office space into GMP laboratories progressed throughout the year, with the first of the laboratories completed by the end of Lorenzo Tallarigo. The Group has made significant strides forward in its commitment to best TTo in Corporate Governance and diversification of talent on the Board.
In November, Dr. Andrew Heath will not be standing for re-election at the AGM having served on the Board since Dricing? Management will be hosting a briefing for analysts via conference call and webcast at BST ET on 15 April A live webcast of the presentation will be available via this link. Oxford Biomedica LSE: OXB is a leading, fully integrated, cell and gene therapy group focused on developing life changing treatments for serious diseases. The Group has created a valuable proprietary portfolio of gene and cell therapy product candidates in the areas of oncology, ophthalmology, CNS disorders and liver diseases. Oxford Biomedica is based across several locations in Oxfordshire, UK and employs more than people. Further information is available at www.
I was first attracted to the Company by its strong purpose and great technology.
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Cell and gene therapies have the potential to be curative for many untreated diseases and to be able to play my part in realising this potential is my duty. It has been a challenging time to assume my role, as our organisation has found new ways of working. Face to face contact has been kept to a minimum for the right reasons, and I thank the Board and the wider OXB team, key opinion leaders and investors for helping me to gain an in-depth understanding of the business.
The pandemic response has both tested and fortified that culture. We pride ourselves on our core values including delivering innovation with integrity.
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Our ability Usse deliver the Oxford AstraZeneca COVID vaccine in the most challenging of circumstances given global demand, has impressed me and has demonstrated that these values run deep through our organisation. This has been achieved whilst continuing to execute the underlying Group strategy, and I give my Usd and appreciation to the Should Driving Be Allowed To Use Cell Phones While Driving? for continuing to deliver on all fronts whilst adapting to new working environments.
Utilising our capabilities to play our part against one of the biggest challenges humankind has recently faced is inspirational and all stakeholders of OXB are, justifiably, proud to be involved in this effort. During the year we also implemented a Group-wide bonus scheme to ensure all staff benefit from the Group achieving its objectives.
Our Strategy OXB continues to deliver on its core strategy of being the leading provider of lentiviral based vectors for cell and gene therapy companies, growing our customer base and service. Significant value to stakeholders can also be provided by applying our knowledge to our own therapeutic products.
The Board realises that the re-balancing of the Group towards products in this way is not easy, as we wish to first build on the CDMO momentum, but given the medical need and the number of nascent technologies and therapeutic programmes using lentiviral based vectors, we are committed to making it happen over time and as opportunities arise. We will accelerate this effort, and retain and build upon our leadership role in this space. It is also clear, through our Oxford AstraZeneca COVID vaccine efforts, that our manufacturing capabilities and state of the art facilities are inherently valuable, and there is the opportunity to leverage these capabilities and facilities to help more partners. We shall be pursuing more partnerships in these adjacencies.
Governance The role of boards in ensuring the societal impact, sustainability and viability of businesses has never been more critical than in the uncertain times of ]
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