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An international team of scientists has developed new methods for the enrichment and analysis of nuclear DNA from sediments, and applied them to cave deposits in Europe and Siberia dated to between approximatelyand 50, years ago.

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Vernot et al. Image credit: Tyler B. Skeletal remains are important sources of Pleistocene hominin DNA, but are rarely recovered at archaeological sites. Mitochondrial DNA mtDNA has been retrieved from cave sediments, but provides limited value for studying population relationships.

Analysis Of Socrates Image Of The Cave

Although nuclear DNA contains far more information, its retrieval from sediments presents substantial challenges. To address these challenges, Dr. Benjamin Vernot from the Department of Evolutionary Genetics at the Max-Planck-Institute for Evolutionary Anthropology and his colleagues developed methods to recover, enrich and analyze nuclear DNA from cave sediments. Vernot said. They detected a population replacement in Spain approximatelyyears ago, accompanied by a turnover of mtDNA.

They also identified two radiation events in Neanderthal history during the early part of the Late Pleistocene.

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The findings were published in the journal Science. Unearthing Neanderthal population history using nuclear and mitochondrial DNA from cave sediments.

Analysis Of Socrates Image Of The Cave

Science, published online April 15, ; doi; ]

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