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Linda N. Smucny J. Evaluation of the patient with dyspepsia. J Fam Pract ; Flynn CA. Evaluation and treatment of adults with gastro-esophageal reflux disease. A trial of test-and-treat strategy for Helicobacter pylori positive dyspeptic patients in general practice. Intern J Clin Pract ; Evaluation of the dyspeptic patient: a cost utility study. Kurata J, Nogawa A.

Helicobacter Pylori Literature Review - shall simply

Abstract Background In general, all virulence factors of Helicobacter pylori H. However, recent studies have shown that the homB gene is one of the virulence genes that affects the severity of the clinical results of this bacterium. Methods The main purpose of this study was to investigate the relationship between the presence of homB gene in H. In the present study, we conducted a systematic search to collect all articles related to the effect of homB-positive strains on clinical outcomes. Finally, 12 eligible studies according to our criteria were included in this meta-analysis and the effect of homB gene on gastric ulcer and gastric cancer diseases was evaluated by summary odds ratio OR. Results Current results showed that the homB-positive strains significantly increase the risk of peptic ulcer OR 1. Moreover, we observed a positive association between the homB gene and risk of gastric cancer OR 2. In addition, based on subgroup analysis, it was found that the presence of this gene in H. Conclusions Overall, in the present study we found that homB gene is responsible for the progressing of primary infection to severe complications, in particular peptic ulcer in western countries and gastric cancer in Asian countries. Helicobacter Pylori Literature Review Helicobacter Pylori Literature Review

1 INTRODUCTION

Pylori [1]. InH. Nevertheless, recent epidemiologic and clinical studies have proved Helicobacter Pylori Literature Review HPI is the main cause for gastric and duodenal diseases. Additionally, HPI has been linked to the pathogenic development of gastric adenocarcinoma [3]the second leading cause of cancer-related death [4]. Acute HPI may appear as an acute gastritis or nausea [5]. Individuals infected with H. The pyloric antrum inflammation leads to duodenal ulcers, while inflammation of the corpus leads to gastric ulcers and gastric carcinoma [8].

Helicobacter Pylori Literature Review

A study showed that HPI was related to gastric cancer and the risk of developing gastric cancer was reduced from 1. In addition, H. However, the clinical checks of most of these non-stomachic diseases do not include HPI screening check due to the controversial and unclear HPI association.

Helicobacter Pylori Literature Review

This review summarizes some previous studies conducted before exploring possible associations between HIP and other diseases, to identify diseases that could use HPI as their clinical indicators. In total, 2, articles published from January to December were covered, which report potential relations between http://pinsoftek.com/wp-content/custom/summer-plan-essay/lady-with-the-pet-dog.php and some diseases. There were different diseases Helicobacter Pylori Literature Review symptoms extracted from the literatures, and their detailed information is listed in the Supplementary Data, including the disease name, category, status of association with HPI and the number of supporting references. Also, these diseases were classified based on the human body system they were related to.

Helicobacter Pylori Literature Review

In total, 1, articles Positive HPI affections were also found in atherosclerosis and myocardial ischemia, Alzheimer disease, Parkinson disease, chronic urticarial, and diabetes mellitus. Negative affections were observed in immune response, including asthma, allegic rhinitis, and digestive diseases that are related to peptic acid secretion e.

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Liver cirrhosis, anemia, idiopathic thrombocytopenic purpura, cerebral infarction, hyperemesis gravidarum, and obesity were reported to have controversial HPI associations. HPI was found in HPI is recognized as a clinical marker for the risk of gastric cancer. It has been shown that HPI could induce gastric cancer through multiple pathogenic steps []. Recently, it was found that patients with chronic gastritis caused by HPI have a three Helicobacter Pylori Literature Review greater risk of developing gastric cancer compared with control groups without HPI [18]. HPI causes chronic gastritis with a mucosal infiltration caused by inflammatory cells [19].]

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